FREQUENCY OF TWIN PREGNANCIES FOLLOWING RENAL-TRANSPLANTATION

Objective: To evaluate the incidence of twin pregnancy among renal-tra nsplanted women. Methods: A retrospective review based on three nation al inquiries. A computer literature search of the Medline system was d one. Only reports of series were included. For statistical analysis th e probability of having a twin pregnancy was assumed to be 0.012. Main Outcome Measures: Incidence of twin pregnancy in women after renal tr ansplantation. Results: There were 7 sets of twins among 153 pregnanci es reported in the national inquiry group (4.57%). Thus, the overall i ncidence of twin pregnancy in these women was 1 in 22 pregnancies. The frequency of twinning in series reporting pregnancies after renal tra nsplantation was 1.84%, a figure statistically greater than the expect ed number of twins (P = 0.001). Conclusions: The frequency of twin pre gnancy appears to be increased among renal-transplanted women.