IRON NUTRITURE IN ELDERLY INDIVIDUALS

The purpose of this review is to examine current research on the iron status of the elderly and factors that influence the body burden of ir on. Studies of noninstitutionalized elderly individuals report mean ir on intakes that meet current Recommended Dietary Allowances for iron. Dietary practices that may decrease iron bioavailability, and hence ir on stores in the body, include low intakes of ascorbic acid or high in takes of calcium, and decreased consumption of highly available iron f rom meat, fish, and poultry. Although not well documented, the effect of age on iron absorption and iron excretion appears to be small, and body stores of iron increase with age. It is difficult to estimate the prevalence of iron deficiency in elderly persons, because impaired ir on status can be the result of iron deficiency or chronic disease. Fur ther study is necessary to determine whether red blood cell ferritin a nd serum transferrin receptors may be useful biochemical markers to di fferentiate the anemia of chronic disease from iron deficiency anemia. Hereditary hemochromatosis is a genetic disease that greatly increase s the body burden of iron and the risk of hepatic disease among homozy gotes. Because iron deficiency or iron excess may impair health, the r ole of icon in diseases associated with aging such as depressed immune response, neurological dysfunction, cancer, and heart disease is disc ussed.