Background: Gastrointestinal tumors are relatively uncommon in infants
and children, and the histologic diagnoses differ from those seen in
an adult practice. Furthermore, the clinical presentation of such tumo
rs is quite variable. Methods: We reviewed the records of 39 pediatric
patients who had been treated for tumors of the alimentary tract at o
ur hospital over the past 20 years. The symptoms. physical findings, t
reatments, and outcomes are tabulated and discussed. Results: Non-Hodg
kin's lymphoma was the predominant diagnosis. It was found in 22 child
ren, and the survival rate was 60%. Other malignant tumors found in th
is pediatric series included colorectal carcinoma in four patients and
gastric leiomyosarcoma in one. The outcomes of these patients were po
or; four of the children have died, and one girl remains alive with ex
tensive disease. Benign lesions included neurogenic tumors (n = 5), in
flammatory pseudotumors (n = 3), hemangiomas (n = 2), teratoma and car
cinoid (n = 1 each). These tumors were ultimately cured, with one exce
ption, after surgical resection. Conclusions: Gastrointestinal tumors
in children cover a broad spectrum of benign and malignant varieties a
nd stem from conditions that differ significantly from those observed
in adults. While treatment varies according to diagnosis, most patient
s respond best to complete resection of the primary tumor.