Objective: To determine the causes of weight loss in nursing home resi
dents. Design: Retrospective chart review of all weights over the prev
ious 6 months and an in-depth examination of all residents who lost 5
or more pounds over that period. Setting: A for-profit community nursi
ng home in an urban area. Subjects: All residents who had been in the
nursing home for 3 or more months. Their mean age was 80.1 years, and
89% were female. Results: Weight loss of 5 pounds or more occurred in
19% of subjects. Only 15% of subjects had lost 5% of body weight, and
4% had lost more than 10% of their body weight. Depression accounted f
or 36% of the weight loss. Other causes of anorexia included medicatio
ns, psychotropic drug reduction, swallowing disorders, paranoia, demen
tia with apraxia, gallstones, and obsessive-compulsive disorder. Incre
ased energy utilization as a cause of weight loss was seen in two resi
dents who wandered incessantly, one with tardive dyskinesia and one wi
th chronic obstructive pulmonary disease. Dehydration was the cause of
weight loss in two residents, and one resident had intentional weight
loss for obesity. Cancer was the cause of weight loss in two resident
s. Four of 30 residents had more than one cause of weight loss. One of
25 tube-fed residents displayed weight loss. Conclusions: A single ca
use of weight loss can be identified in most nursing home residents. D
epression is the most common cause of weight loss. Psychotropic drug r
eduction may cause weight loss. The majority of causes of weight loss
in a community nursing home are potentially treatable.