AGE, ENVIRONMENTAL-FACTORS AND DRUG-METABOLISM

Authors
OMAHONY MS WOODHOUSE KW
Citation
Ms. Omahony et Kw. Woodhouse, AGE, ENVIRONMENTAL-FACTORS AND DRUG-METABOLISM, Pharmacology & therapeutics, 61(1-2), 1994, pp. 279-287
Citations number
83
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Pharmacology & therapeutics → ACNP
ISSN journal
01637258
Volume
61
Issue
1-2
Year of publication
1994
Pages
279 - 287
Database
ISI
SICI code
0163-7258(1994)61:1-2<279:AEAD>2.0.ZU;2-M
Abstract
Both ageing and the environment have a significant impact on xenobioti c metabolism. Furthermore, there is some evidence from in vivo studies that the elderly respond to environmental changes to a lesser degree than younger individuals. This article reviews the available evidence and concentrates on possible underlying mechanisms.