The incidence of post-lumbar puncture headache has been shown to be re
duced by using a higher-gauge (smaller-bore) needle and orienting the
needle bevel parallel to the dural fibers. Incidence of headache is th
e same in patients given bed rest as in patients who are mobilized imm
ediately. Cerebrospinal fluid (CSF) examination of patients with seizu
res of unclear cause is indicated. However, pleocytosis must be ruled
out by clinical evaluation and CSF studies. Although lumbar puncture i
s often advocated for patients presenting with dementia, it usually is
not helpful in finding a specific cause if the dementia is long-stand
ing.