ABNORMAL GLYCOSYLATION OF MOTOR-NEURONS WITH N-ACETYL-D-GALACTOSAMINEIN A CASE OF SUBACUTE MOTOR NEURONOPATHY ASSOCIATED WITH LYMPHOMA

Lectins, glycine max (SBA) and Vicia villosa (VVA), which identify ter minal N-acetyl-D-galactosamine (GalNAc), stained the motor neurons of a patient with subacute motor neuronopathy associated with neoplastic angioendotheliosis. In normal controls and in patients with other neur ological disorders including amyotrophic lateral sclerosis, neither le ctin stained motor neurons. Abnormal glycosylation of motor neurons wi th terminal galNAc may be associated with the pathogenesis of subacute motor neuronopathy in this patient.