The effects of nicotine on human cooperative responding in abstinent m
ale smokers were examined, During episodes occurring at random times t
hrough a session, concurrently available cooperative and independent r
esponses were maintained by points exchangeable for money. Cooperative
responses simultaneously added points to counters marked ''Your Earni
ngs'' and ''Other's Earnings'' only if the subject's and another perso
n's responses ostensibly coincided. Independent responses added points
only to the counter marked ''Your Earnings''. After the first daily s
ession abstinent subjects smoked ad libitum, received either 0, 2 or 4
mg nicotine gum or abstained from smoking. Increases from this first
session in time allocated to the cooperative response option, proporti
on of cooperative responses and cooperative response rate were signifi
cantly greater following ad libitum smoking or acute administration of
4 mg nicotine. No effects of nicotine abstinence were observed on ind
ependent response rate. These results suggest effects on sociability m
ay maintain nicotine use and increase relapse risk in abstinent smoker
s.