Hypophyseal apoplexy is not always easy to confirm morphologically or
analytically. We present a patient with Cushing's syndrome due to hypo
physeal apoplexy and optochiasmic pachyarachnoiditis which produced se
rious visual alterations. The adenoma necrosized behind an area of hyp
ophyseal apoplexy which cured the patient's Cushing's disease. The sec
ond case was admitted with hypophyseal apoplexy, presenting hypophysea
l tumoration with signs of hemorrhage and subsequent panhypopituitaris
m.