We reported 76 cases of HFSR during two years (1992-1993) in the Arden
nes area. The patients lived in the northeast part of French Ardennes,
along the valley of Semoy and Meuse. Some activities are the main ris
k factors : chop the trees in the forest, certains ways of building, h
andling firewood stock pilled, exposure to dust. Clinical symptoms wer
e no more severe than usual. Only one patient had to be dialysed. Algi
c syndrome can be absent in 17%, also renal insufficiency in 45,2%. Du
ring the first week, thrombopenia is always noted, and proteinurie in
68,8% of cases.