A CATALYTIC ANTIBODY ELICITED BY A HAPTEN OF TETRAHEDRAL CARBON-TYPE

Authors
KITAZUME T TSUKAMOTO T YOSHIMURA K
Citation
T. Kitazume et al., A CATALYTIC ANTIBODY ELICITED BY A HAPTEN OF TETRAHEDRAL CARBON-TYPE, Journal of the Chemical Society, Chemical Communications, (11), 1994, pp. 1355-1356
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
11
Year of publication
1994
Pages
1355 - 1356
Database
ISI
SICI code
0022-4936(1994):11<1355:ACAEBA>2.0.ZU;2-N
Abstract
A monoclonal antibody, elicited by a alpha,alpha,alpha',alpha'-tetrafl uoroketone hapten, acted as an enzyme-like catalyst for the hydrolysis of an analogous carbonate, demonstrating that the difluoromethylene u nit can been used as an isostere and isoelectronic mimic for the oxyge n atom in an ether.