GIANT-CELL FIBROBLASTOMA WITH PIGMENTED DERMATOFIBROSARCOMA PROTUBERANS COMPONENT

Citation
M. Zamecnik et M. Michal, GIANT-CELL FIBROBLASTOMA WITH PIGMENTED DERMATOFIBROSARCOMA PROTUBERANS COMPONENT, The American journal of surgical pathology, 18(7), 1994, pp. 736-740
Citations number
33
Categorie Soggetti
Pathology,Surgery
ISSN journal
01475185
Volume
18
Issue
7
Year of publication
1994
Pages
736 - 740
Database
ISI
SICI code
0147-5185(1994)18:7<736:GFWPDP>2.0.ZU;2-H
Abstract
A unique case of giant-cell fibroblastoma that contained a pigmented d ermatofibrosarcoma component (Bednar tumor) is described. The melanin pigmented dendritic cells found in the dermatofibrosarcoma component w ere round or spindle-shaped and had bipolar extensions. They were S-10 0 protein positive. Our case indicates the close histogenetic relation ship between giant-cell fibroblastoma and dermatofibrosarcoma protuber ans. The occurrence of the pigmented melanin-laden dendritic cells in our tumor further substantiates the theory that Bednar tumor is a pigm ented variant of dermatofibrosarcoma protuberans.