Sa. Madreperla et al., CLINICOPATHOLOGICAL CORRELATION OF A MACULAR HOLE TREATED BY CORTICALVITREOUS PEELING AND GAS TAMPONADE, Ophthalmology, 101(4), 1994, pp. 682-686
Purpose: To study the histopathology of a stage III macular hole that
had been treated by vitrectomy with cortical vitreous and epicortical
vitreous membrane peeling and gas tamponade. Methods: The light and el
ectron microscopic features of a treated macular hole was studied. Res
ults: A 16-mu m-wide break was present in the external limiting membra
ne. This was sealed by Muller cell processes. Photoreceptors adjacent
to the healed defect appeared normal. No cystoid macular edema was pre
sent. Conclusion: Cortical vitreous peeling and gas tamponade can allo
w the macular hole to settle and the edges to re-approximate. The resi
dual defect can be sealed by Muller cells.