MILK-PRODUCTION IN COWS WITH ENDOTOXIN-INDUCED MASTITIS TREATED WITH ISOTONIC OR HYPERTONIC SODIUM-CHLORIDE SOLUTION

Milk production was monitored in 16 cows for 6 milkings after intramam mary infusion of 1 mg of endotoxin in a single forequarter. The cows w ere randomly assigned to 1 of 2 treatment groups; 8 cows were created with isotonic saline solution and 8 cows were treated with hypertonic saline solution. Saline solutions were administered Iv (5 ml/kg of bod y weight) 4 hours after infusion of endotoxin. Mean cumulative change in milk yield and interval change in milk yield were greater in cows t reated with isotonic saline solution than in cows treated with hyperto nic saline solution. Significant differences between treatment groups were not defected.