CYTOTOXIC CONSTITUENTS OF SORBARIA-SORBIFOLIA VAR STELLIPILA

Authors
KIM DK CHOI SH LEE JO RYU SY PARK DK SHIN DH JUNG JH PYO SK LEE KR ZEE OP
Citation
Dk. Kim et al., CYTOTOXIC CONSTITUENTS OF SORBARIA-SORBIFOLIA VAR STELLIPILA, Archives of pharmacal research, 20(1), 1997, pp. 85-87
Citations number
11
Categorie Soggetti
Biology
Journal title
Archives of pharmacal research → ACNP
ISSN journal
02536269
Volume
20
Issue
1
Year of publication
1997
Pages
85 - 87
Database
ISI
SICI code
0253-6269(1997)20:1<85:CCOSVS>2.0.ZU;2-H
Abstract
The acivity-guided fractionation upon the MeOH extract of the aerial p arts of Sorbaria sorbifolia var. stellipila led to the isolation of tw o cucurbitacin-compounds, cucurbitacin D and cucurbitacin F, as active principles. Two compounds were shown to exhibit significant cytotoxic ity against cultured human tumor cell lines, A-549, SK-OV-3, SK-MEL-2, XF-498, and HCT 15.