A CASE OF HEPATOCELLULAR-CARCINOMA CONSISTING OF 2 SOLITARY POORLY DIFFERENTIATED POLYCLONAL INTRAHEPATIC TUMOR NODULES

Authors
YAMAMOTO M MATSUDA M MIURA K NAGAHORI K MATSUMOTO Y
Citation
M. Yamamoto et al., A CASE OF HEPATOCELLULAR-CARCINOMA CONSISTING OF 2 SOLITARY POORLY DIFFERENTIATED POLYCLONAL INTRAHEPATIC TUMOR NODULES, Journal of gastroenterology, 29(3), 1994, pp. 357-361
Citations number
NO
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Journal of gastroenterology → ACNP
ISSN journal
09441174
Volume
29
Issue
3
Year of publication
1994
Pages
357 - 361
Database
ISI
SICI code
0944-1174(1994)29:3<357:ACOHCO>2.0.ZU;2-T
Abstract
Two intrahepatic solitary tumors consisting of poorly differentiated h epatocellular carcinoma (HCC) were identified as polyclonal HCC nodule s by analysis of the pattern of integration of hepatitis B viral DNA i nto nuclear DNA. After the removal of each nodule by partial liver res ection, recurrent multiple tumors appeared within 10 months post-opera tively. The findings in this case suggest that the effectiveness of re duction surgery for intrahepatic multiple tumors is limited in solitar y multicentric HCC that consists of poorly differentiated HCC.