Aj. Barsky et al., PSYCHIATRIC-DISORDERS IN MEDICAL OUTPATIENTS COMPLAINING OF PALPITATIONS, Journal of general internal medicine, 9(6), 1994, pp. 306-313
Objective: To determine the prevalence of psychiatric disorders in amb
ulatory patients undergoing Holter monitoring to evaluate palpitations
. Design: Patients referred for 24-hour ambulatory electrocardiographi
c (ECG) monitoring were studied with a structured diagnostic interview
and self-report questionnaires prior to monitoring. Setting: Holter l
aboratory of a large academic medical center. Patients and other parti
cipants: One hundred forty-five consecutive patients complaining of pa
lpitations and 70 asymptomatic non-patient volunteers. Outcome measure
s: DSM-III-R psychiatric diagnoses. Results: Forty-five percent (44.8%
) of the participants had at least one lifetime anxiety or depressive
disorder and 24.8% had at least one current (one month) disorder. The
lifetime prevalence of panic disorder was 27.6%, and that of major de
pression was 20.8%. Current prevalence rates showed a similar pattern;
the current prevalence of panic disorder was 18.6%. Panic disorder an
d somatization disorder symptoms were significantly more prevalent in
the palpitation group than in the general medical clinic at the same h
ospital. Patients with a psychiatric diagnosis were more likely to rep
ort cardiac symptoms during monitoring than were those without psychia
tric disorder, and more commonly described their symptoms as ''poundin
g'' and reported faintness, lightheadedness, and vertigo. Although car
diac histories and ECG results were no more serious, the patients with
Psychiatric diagnoses rated their overall health status as significan
tly worse. Conclusions: Almost half of palpitation patients referred f
or Holter monitoring have a psychiatric disorder. More than a fourth h
ave lifetime panic disorder and a fifth have had panic attacks in the
month before monitoring.