THE RELATIONSHIP BETWEEN TOTAL MOTILE SPERM COUNT AND THE SUCCESS OF INTRAUTERINE INSEMINATION

Objectives: To determine if the total motile sperm count is predictive of IUI success and to apply life-table analysis to a large database o f IUI procedures. Design: Contingency table and life-table analyses we re used to analyze a large group of couples (n = 546) undergoing 1,205 cycles of therapeutic IUI with husband's sperm. Setting: Clinical inf ertility practice at a medical school referral center. Patients: Five hundred forty-six couples with varying etiologies of infertility. Resu lts: There was a trend toward an increasing percentage of conception w ith increasing total motile sperm count. Significance was reached when the total motile sperm count used for IUI exceeded 20 X 10(6). The cu mulative pregnancy rate calculated from this data reached 52% after th e sixth attempted cycle of IUI.