DIRECT ENANTIOSELECTIVE SYNTHESIS OF SYN-1,3-DIOLS BY THE REACTION OFALDEHYDES WITH ENOL SILYL ETHERS IN THE PRESENCE OF A CHIRAL BORANE COMPLEX - SUCCESSIVE ASYMMETRIC ALDOL REACTION AND ASYMMETRIC REDUCTIONWITH ONE PROMOTER

Authors
KANEKO Y MATSUO T KIYOOKA S
Citation
Y. Kaneko et al., DIRECT ENANTIOSELECTIVE SYNTHESIS OF SYN-1,3-DIOLS BY THE REACTION OFALDEHYDES WITH ENOL SILYL ETHERS IN THE PRESENCE OF A CHIRAL BORANE COMPLEX - SUCCESSIVE ASYMMETRIC ALDOL REACTION AND ASYMMETRIC REDUCTIONWITH ONE PROMOTER, Tetrahedron letters, 35(24), 1994, pp. 4107-4110
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
24
Year of publication
1994
Pages
4107 - 4110
Database
ISI
SICI code
0040-4039(1994)35:24<4107:DESOSB>2.0.ZU;2-C
Abstract
A stoichiometric amount of the chiral borane 1 turned out to successiv ely promote the asymmetric aldol reaction of aldehydes with enol silyl ethers and the following asymmetric reduction in one pot to afford sy n-1,3-diols with high enantioselectivity.