A STUDY ON SONODYNAMIC THERAPY ANTITUMOR EFFECT OF NOVEL SONODYNAMIC COMPOUNDS UNDER ULTRASOUND

Authors
SUZUKI T KAMADA S YOSHIDA Y UNNO K
Citation
T. Suzuki et al., A STUDY ON SONODYNAMIC THERAPY ANTITUMOR EFFECT OF NOVEL SONODYNAMIC COMPOUNDS UNDER ULTRASOUND, Heterocycles, 38(6), 1994, pp. 1209-1211
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
38
Issue
6
Year of publication
1994
Pages
1209 - 1211
Database
ISI
SICI code
0385-5414(1994)38:6<1209:ASOSTA>2.0.ZU;2-8
Abstract
Diacetylhematoporphyrin-mitomycin C conjugate ( diAc-Hp-MMC ) (1) prep ared by a condensation of diacetylhematoporphyrin with MMC in the pres ence of N, N- dimethylaminopyridine and dicyclohexylcarbodiimide, and two of the pyridocarbazole derivatives (8) and (9) were provided for s onodynamic compounds and these compounds were found to show excellent cell-killing effect, comparing to those of the known sonodynamc compou nd hematoporphyrin, Hp 2HCl (2), Di-Ac-Hp (3), Hp-Co (4), Hp-Fe (5), A crinol ( 6) and MMC (7).