Gb. Jones et al., BIFUNCTIONAL ANTITUMOR AGENTS - PYRROLO-[9,10]PHENANTHRENES AS INTERCALATIVE DRUG-DELIVERY VEHICLES, Heterocycles, 38(6), 1994, pp. 1221-1224
The preparation of a pyrrolo[9, 10]phenanthrene nucleus is described.
The utility of the template as a potential DNA intercalating drug deli
very system is demonstrated by synthesis of a derived bis chloroethyla
mine alkylating system.