MICELLE FORMATION IN SODIUM TAUROCHOLATE-LECITHIN-WATER MIXTURES

Tensiometric and conductometric methods were used to study micelle for mation in aqueous solutions of sodium taurocholate, lecithin (in the p resence of ethanol), and their mixtures with variation of the sodium t aurocholate concentration. Two types of isotherms of the surface tensi on were obtained: the usual type and with a minimum. Computer processi ng of the results of the measurements yielded characteristics of the a dsorption layers of sodium taurocholate (maximum adsorption, area occu pied by a molecule on the water-air interface), as well as the critica l micelle concentration (CMC) of solutions of the surfactants and mixt ures studied and the degree of binding of counterions in the micelles. Lipid-detergent interactions of the components of the mixtures are di scussed.