INTRACAPILLARY GLOMERULAR METASTASES IN A NEPHRECTOMY SPECIMEN REMOVED FOR IPSILATERAL RENAL-CELL CARCINOMA

A case of intraglomerular metastases observed in a nephrectomy specime n removed for primary renal cell carcinoma is reported. The intraglome rular metastases arose by dissemination of malignant cells into the sy stemic circulation via invasion of the renal veins. Intraglomerular me tastases are therefore an indicator of malignant dissemination which i n turn should be associated with a poor prognosis. It is recommended t hat in nephrectomies undertaken for primary renal cell carcinoma at le ast one random block of renal cortex should be examined to confirm or exclude intraglomerular metastases.