Objective: Our objective was to assess airborne latex allergen exposur
e in the workplace of a hospital laboratory technician with occupation
al latex sensitization and repeated anaphylactic episodes from this. H
er allergic manifestations had cleared only when coworkers changed to
powder-free later gloves. Therefore a labolatory still using powdered
later gloves was selected for comparative airborne latex sampling. Des
ign: The design was a survey. Setting: We used a hospital hematology l
aboratory, and a biochemistry laboratory was used for comparison. Part
icipants: The index case with latex allergy is described. An average o
f 10 employees worked on the day shift in the same laboratory, and 10
employees worked in the biochemistry laboratory studied. Main outcome
measure: Airborne latex allergen levels obtained by high airflow area
sampling were compared in the laboratory using powder-free latex glove
s and in the laboratory using powdered latex gloves. Results: Levels w
ere below the level of detection (<0.02 ng/m(3) of latex allergen) in
the laboratory using powder-free latex gloves brit ranged from 39 to 3
11 ng/m(3) in the laboratory using powdered gloves. Conclusions: Airbo
rne later allergen is produced with use of powdered latex gloves. Such
usage by coworkers may provoke respiratory and anaphylactic response
to latex in sensitized subjects. Use of powder-free gloves by coworker
s may enable such patients to continue work in their trained professio
n and may prevent measurable airborne latex exposure. Affected patient
s, however, still need to avoid direct latex contact.