HISTOENZYMATIC STUDY OF HUMAN RENAL TISSUE PRESERVATION .1. PROXIMAL TUBULAR GLUCOSE-6-PHOSPHATASE IS CORRELATED WITH TRANSPLANT EVOLUTION

Authors
CHAMLIAN A BENKOEL L DIMARINO V BRISSE J COPPENS R",DEECKENBRUGGE,"CASANOVA P
Citation
A. Chamlian et al., HISTOENZYMATIC STUDY OF HUMAN RENAL TISSUE PRESERVATION .1. PROXIMAL TUBULAR GLUCOSE-6-PHOSPHATASE IS CORRELATED WITH TRANSPLANT EVOLUTION, Cellular and molecular biology, 40(4), 1994, pp. 527-534
Citations number
37
Categorie Soggetti
Cytology & Histology",Biology
Journal title
Cellular and molecular biology → ACNP
ISSN journal
01455680
Volume
40
Issue
4
Year of publication
1994
Pages
527 - 534
Database
ISI
SICI code
0145-5680(1994)40:4<527:HSOHRT>2.0.ZU;2-W
Abstract
Glucose-6-phosphatase was tested histochemically as a gluconeogenesis marker of ischemia-reperfusion injury of proximal tubular cells in hum an renal transplants. Histochemical enzyme activity, histology and tra nsplantation conditions (preservation solution, cold and warm ischemia time, donor age), were compared to renal transplant evolution. Neithe r histology nor transplantation conditions were correlated with renal transplant evolution. Only glucose-6-phosphatase activity was signific antly correlated with transplant evolution and could be used as a more sensitive marker than histology for the detection of ischemia-reperfu sion injury of proximal tubules.