CLINICOPATHOLOGICAL FINDINGS IN HUMAN AUTOPSY EYES WITH AN ANIS CIRCULAR LENS

Purpose: To evaluate the long-term performance of the Anis circular in traocular lens (IOL). Setting: Center for IOL Research, Storm Eye Inst itute, Charleston, South Carolina. Materials: Fifteen human autopsy ey es with an Anis circular IOL submitted between 1985 and 1993 were eval uated. The eyes were sectioned at the equatorial plane, and the anteri or segment containing the capsular bag and the IOL was photographed fr om the posterior perspective. Fixation, centration, capsular bag shape , zonular damage, central posterior capsule opacification (PCO), and S oemmering's ring formation were analyzed. The results were compared wi th those of a control group comprising human autopsy eyes with a one-p iece (n=15) or three-piece (n=15) poly(methyl methacrylate) IOL with a C-loop design. Results: All 15 Anis IOLs showed symmetrical in-the-ba g fixation. Mean decentration in the Anis IOL eyes was significantly l ower than in the control eyes (P=.02). Eyes with the Anis IOL had fewe r zonular defects (P=.0005) and a better circular extension of the cap sular bag (P=.003). There were no statistically significant difference s in PCO (P=.29) or Soemmering's ring formation (P=.67).Conclusion: Th e Anis IOL with a circular haptic design had better centration and cap sular bag morphology than the control eyes, although a difference in P CO and Soemmering's ring formation could not be shown.