Va. Lazzell et al., THE INCIDENCE OF MASSETER MUSCLE RIGIDITY AFTER SUCCINYLCHOLINE IN INFANTS AND CHILDREN, Canadian journal of anaesthesia, 41(6), 1994, pp. 475-479
To determine whether the incidence of masseter muscle rigidity is affe
cted by the anaesthetic induction sequence, we prospectively studied f
or ten months the anaesthetic course in 5,641 infants and children who
received muscle relaxation to facilitate tracheal intubation. The ana
esthetic induction sequence consisted of intravenous sodium thiopenton
e (STP) 5 mg . kg(-1) alone, halothane induction alone 1-4%, or haloth
ane followed by STP Inhalational inductions with halothane included ni
trous oxide and oxygen. Tracheal intubation was facilitated by either
intravenous succinylcholine (Sch) at least 1.5 mg . kg(-1) or by a non
-depolarizing muscle relaxant. The induction sequence and all episodes
of MMR were recorded. Ninety percent of the patients received Sch and
10% received a non-depolarising agent. Of those who received Sch, 88%
(5,064 patients) were anaesthetised with STP and 12% (607 patients) w
ere anaesthetised with halothane alone or halothane followed by STP Ma
sseter muscle rigidity was defined clinically by the transient inabili
ty to distract the mandible from the maxilla such that the mouth could
not be opened or could only be opened with force. No children anaesth
etised with STP followed by Sch developed MMR. One child (0.9%) develo
ped MMR after halothane and Sch and two developed MMR after halothane,
STP and Sch (0.4%). The incidence of MMR after Sch was less with STP
than with halothane alone or with halothane and