Low energy laser (LEL) is a widely used treatment for a variety of mus
culoskeletal disorders although convincing documentation of the effect
is missing. We have examined the LEL effect on Rheumatoid Arthritis (
RA) in a double blind placebo controlled study. Twenty-two patients co
mpleted the study (10 receiving LEL treatment) according to the protoc
ol. A significant effect on pain score was found due to LEL treatment,
but when data were corrected for disease variation the effect disappe
ared. No effect of LEL could be demonstrated on the other assessed var
iables: grip strength, morning stiffness, flexibility, erythrocyte sed
imentation rate (ESR), C-reactive protein (CRP). In conclusion, we did
not find that LEL had any clinically relevant effects on RA.