ALPHA-2-HS-GLYCOPROTEIN GENE-FREQUENCIES IN BASQUES

Authors
AGUIRRE A SANZ P OSABA L MANZANO C ESTOMBA A MAZON L DELARUA C VICARIO A
Citation
A. Aguirre et al., ALPHA-2-HS-GLYCOPROTEIN GENE-FREQUENCIES IN BASQUES, Human heredity, 44(4), 1994, pp. 220-224
Citations number
33
Categorie Soggetti
Genetics & Heredity
Journal title
Human heredity → ACNP
ISSN journal
00015652
Volume
44
Issue
4
Year of publication
1994
Pages
220 - 224
Database
ISI
SICI code
0001-5652(1994)44:4<220:AGIB>2.0.ZU;2-N
Abstract
The genetic polymorphism of human alpha(2)-HS-glycoprotein (AHSG) was analyzed in a sample of 736 native individuals from the three province s of the Basque Autonomous Community (Guipuzcoa, Vizcaya and Alava). T he Basque population shows the highest frequency of the allele AHSG3 described to date in European populations. The same is not true for th e frequency of allele AHSG2, which fits well into the genocline descr ibed in Europe, in accordance with the adaptive hypothesis.