THE ACUTE EFFECTS OF A RAPID MEDICAL DETOXIFICATION UPON DYSPHORIA AND OTHER PSYCHOPATHOLOGY EXPERIENCED BY HEROIN ABUSERS

Self-reported dysphoria, personality disorder traits, and subjective o pioid withdrawal symptoms were assessed in 30 opioid abusers before an d after a rapid medical detoxification from heroin. Subject exclusion criteria reflected an effort to control for potential sources of affec tive change that were extraneous to the effect of detoxification. Subj ects received few rehabilitative services during their 12-day inpatien t hospitalization, and were not permitted visitors or off-ward privile ges. At the preadmission assessment, they reported elevated levels of dysphoria and personality disorder traits, as well as opioid withdrawa l symptoms. The results indicate that clinically significant declines in symptoms of dysphoria, opioid withdrawal symptoms, and personality disorder traits occur during the course of a rapid medical detoxificat ion. Dysphoric and opioid withdrawal symptom abatement was most pronou nced between the preadmission and admission assessments. These factors should be considered in the clinical diagnosis and treatment, as well as in research about psychiatric comorbidity of these substance abuse rs.