SYNTHESIS OF FUSED 1,2,4-THIADIAZOLES FROM 5-CHLORO-1,2,4-THIADIAZOL-3(2H)-ONES

Authors
LABBE G BUELENS J DEHAEN W TOPPET S FENEAUDUPONT J DECLERCQ JP
Citation
G. Labbe et al., SYNTHESIS OF FUSED 1,2,4-THIADIAZOLES FROM 5-CHLORO-1,2,4-THIADIAZOL-3(2H)-ONES, Tetrahedron, 50(24), 1994, pp. 7019-7028
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
50
Issue
24
Year of publication
1994
Pages
7019 - 7028
Database
ISI
SICI code
0040-4020(1994)50:24<7019:SOF1F5>2.0.ZU;2-4
Abstract
Fused 1,2,4-thiadiazoles (14-18 and 26-31) are conveniently prepared b y reacting the chlorothiadiazolone 12 with omega-aminonitriles and ami noazoles. During these reactions the original thiadiazole ring is open ed and a new, fused thiadiazole rig is formed, probably via a hyperval ent sulfur intermediate. The products derived from the aminoazoles wer e analyzed by X-ray crystallography and found to have structures diffe rent from those published earlier.(7)