PURPOSE: To determine the efficacy of various magnetic resonance (MR)
imaging sequences for the differentiation of adrenal masses. MATERIALS
AND METHODS Fifty-three adrenal masses in 46 patients (adenomas, meta
stases, myelolipomas, hemorrhages, and pheochromocytomas) were evaluat
ed by means of T1-, T2-, and T2-weighted sequences, calculated T2 val
ues, chemical shift imaging techniques, and dynamic contrast material-
enhanced imaging. The Student t test and receiver operating characteri
stic analysis Were used to evaluate the differences in the groups of m
asses. RESULTS: Analysis of the chemical shift-induced signal intensit
y of the adrenal masses and the T2-weighted sequence enabled differen
tiation of adenomas, metastases, and pheochromocytomas. Adenomas and p
heochromocytomas were also differentiated by means of a heavily T2-wei
ghted sequence. Signal intensity values for all masses overlapped. CON
CLUSION: Although a chemical shift imaging technique and a T2-weighte
d sequence helped correctly differentiate among the groups of adrenal
masses, the degree of Overlap suggests that it is still difficult to e
valuate disease m individual patients.