PURPOSE: To define age-specific patterns of distribution of red and ye
llow marrow about the shoulder. MATERIALS AND METHODS: Red and yellow
marrow distribution was reviewed on magnetic resonance images of 189 s
ubjects aged 15-69 years. Double-echo and fast spin-echo, gradient, an
d short inversion time inversion recovery pulse sequences were used. T
he acromion, glenoid, and proximal humeral epiphysis, metaphysis, and
diaphysis in each shoulder were graded semiquantitatively and qualitat
ively. RESULTS: There was a wide variation in the normal pattern of re
d-yellow marrow distribution both among subjects and among locations.
All five anatomic locations showed an orderly progression from greater
to lesser amounts of red marrow with increasing age. Many of the subj
ects had focal subchondral red marrow in the epiphysis, which was asso
ciated with patient age (P = .0001) and gender (P = .04). CONCLUSION:
Knowledge of normal patterns of marrow distribution can prevent their
being misinterpreted as marrow-based disease.