G. Viswanathan et Ptv. Nair, INCREASED SENSITIVITY OF PLATELETS FROM UNSTABLE ANGINA PATIENTS TO ADENOSINE DIPHOSPHATE-INDUCED AGGREGATION, Journal of clinical biochemistry and nutrition, 16(3), 1994, pp. 201-204
ADP-induced platelet aggregation of normal individuals and of patients
with unstable angina were studied. Abnormalities of platelet function
included increased aggregability. The ADP concentration required for
half-maximal aggregation was significantly lower (4.28+/-0.30 muM) in
the unstable angina patients compared with that for normal individuals
(5.24+/-0.15 muM). The results are suggestive of platelet aggregation
as a useful prognostic indicator for unstable angina.