Rh. Poe et al., USE OF FIBEROPTIC BRONCHOSCOPY IN THE DIAGNOSIS OF BRONCHOGENIC-CARCINOMA - A STUDY IN PATIENTS WITH IDIOPATHIC PLEURAL EFFUSIONS, Chest, 105(6), 1994, pp. 1663-1667
We reviewed our experience with 115 patients with pleural effusion in
whom bronchogenic carcinoma was suspected who underwent fiberoptic bro
nchoscopy (FOB) to identify those for whom the procedure was useful. I
n 6 of 12 patients with hemoptysis, 8 of 12 with a mass or infiltrate,
and 8 of 18 with atelectasis with negative fluid cytology and 3 of 7
with cytology positive, FOB was useful in diagnosis. Sixty-six patient
s had an isolated cytology-negative effusion. Seven of 18 with massive
effusion had FOB detecting cancer. Fiberoptic bronchoscopy usually wa
s nondiagnostic in lesser-sized effusions (47 of 48). Using outcome fo
r those with nondiagnostic FOB, we established operating characteristi
cs for the procedure. We conclude that FOB is useful in diagnosing bro
nchogenic carcinoma in such patients when there is hemoptysis, accompa
nying lung mass or infiltrate, atelectasis, the effusion is massive, o
r in cytology-positive effusions without obvious primary tumor. Due to
the low prevalence of bronchogenic carcinoma in patients with effusio
ns of lesser size, we suggest that in this group FOB not be routinely
performed.