WR-1065 AS A CHEMOPROTECTOR IN ADRIAMYCIN CHEMOTHERAPY

Authors
BHANUMATHI P SALEESH ED VASUDEVAN DM
Citation
P. Bhanumathi et al., WR-1065 AS A CHEMOPROTECTOR IN ADRIAMYCIN CHEMOTHERAPY, Cancer letters, 81(2), 1994, pp. 171-175
Citations number
18
Categorie Soggetti
Oncology
Journal title
Cancer letters → ACNP
ISSN journal
03043835
Volume
81
Issue
2
Year of publication
1994
Pages
171 - 175
Database
ISI
SICI code
0304-3835(1994)81:2<171:WAACIA>2.0.ZU;2-H
Abstract
The protective effect of WR-1065 against the side effects of Adriamyci n was studied in tumor bearing mice. It has been noticed that WR-1065 pretreatment improved the Adriamycin toxicities such as increased enzy me levels, pathological lesions in lung, liver and heart and increased rate of lipid peroxidation, without reducing its anticancer property.