CAPILLARY ZONE ELECTROPHORESIS IN PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Capillary zone electrophoresis is a technique that is rapidly gaining popularity in the pharmaceutical industry because of the wide range of compounds applicable to the technique. These range from small biologi cally active molecules through to large nucleotides and proteins. This review outlines the historical development of the technique and some of the basic theory of capillary zone electrophoresis. This is followe d by an explanation of some of the adaptations now being used to enabl e the separation of neutral molecules as well as charged species, and ways of achieving chiral selectivity.