NUCLEAR-MAGNETIC-RESONANCE (NMR) ANALYSIS ON THE SERUM-LIPIDS OF RABBITS INFECTED WITH SCHISTOSOMA-JAPONICUM - OXIDATIVE MODIFICATIONS OF DIENE SYSTEM IN FATTY CHAINS
M. Nishina et al., NUCLEAR-MAGNETIC-RESONANCE (NMR) ANALYSIS ON THE SERUM-LIPIDS OF RABBITS INFECTED WITH SCHISTOSOMA-JAPONICUM - OXIDATIVE MODIFICATIONS OF DIENE SYSTEM IN FATTY CHAINS, International journal for parasitology, 24(3), 1994, pp. 417-419
Proton nuclear magnetic resonance (H-1 NMR) spectroscopy was used to c
haracterize the oxidized products in the serum lipoprotein lipids (LPL
) of rabbits infected with Schistosoma japonicum. The loss of bis-ally
lic and allylic methylenes proton peaks (2.7 and 2.0 p.p.m.) of unsatu
rated systems of the LPL and the appearance of the signals of the conj
ugated diene systems of hydroperoxide (5.43-6.45 p.p.m.) and epidioxid
e (2.45 p.p.m.) of the fatty chains of the serum demonstrated the lipi
ds degradation associated with the Schistosoma infection.