COMPARISON OF THE ANTI-HERPES SIMPLEX VIRUS ACTIVITIES OF PROPOLIS AND 3-METHYL-BUT-2-ENYL CAFFEATE

Authors
AMOROS M LURTON E BOUSTIE J GIRRE L SAUVAGER F CORMIER M
Citation
M. Amoros et al., COMPARISON OF THE ANTI-HERPES SIMPLEX VIRUS ACTIVITIES OF PROPOLIS AND 3-METHYL-BUT-2-ENYL CAFFEATE, Journal of natural products, 57(5), 1994, pp. 644-647
Citations number
21
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
57
Issue
5
Year of publication
1994
Pages
644 - 647
Database
ISI
SICI code
0163-3864(1994)57:5<644:COTASV>2.0.ZU;2-G
Abstract
The in vitro activity against herpes simplex virus type 1 of 3-methyl- but-2-enyl caffeate isolated from poplar buds or prepared by synthesis was investigated. Under conditions of one or multiple multiplication cycles, this compound, which is a minor constituent of propolis, was f ound to reduce the viral titer by 3 log(10), and viral DNA synthesis b y 32-fold.