OPTIMIZED AVERAGING BY ONLINE STATISTICAL VERIFICATION OF RESPONSE INCLINICAL ELECTRODIAGNOSTIC TRIALS

Real time statistical verification of the averaged response in many es tablished electrodiagnostic tests may result in a substantially reduce d number of presented stimuli thus minimising the test's duration and reducing the overall time load on the patient examined. Furthermore, a sufficient number of stimuli may be automatically established in an o bjective statistical way by accounting for the response amplitude and variance, noise amplitude etc., resulting in averages with matching si gnal to noise ratio. A technique of real time statistical verification of the response based upon single trial data analysis was developed a nd verified in clinical electroretinographic (ERG) tests.