LATE RECURRENT METASTASIS IN WILMS-TUMOR

Recurrence of Wilms' tumour after 5 years of disease-free survival is rare. We present the case of a 26-year-old man who had been diagnosed of Wilms' tumour at the age of 6 years treated by surgery, chemotherap y, and radiotherapy and who remained disease free for 8 years, after w hich lung metastases were detected. Second complete remission was atta ined with surgery and chemotherapy and 20 years after initial diagnosi s he again presented with lung metastases, similarly achieving complet e remission with surgery and second-line chemotherapy. The clinical an d biological aspects of late metastasis in this neoplasm are discussed . (C) 1994 Wiley-Liss, Inc.