IDENTIFICATION, CHARACTERIZATION, AND PHYSICAL MAPPING OF 14 POLYMORPHIC SIMPLE SEQUENCE REPEAT MARKERS ON HUMAN-CHROMOSOME-21

Authors
LOWRY SR WILSON K BLAZEJ R CHIU J RINE J OSTRANDER EA
Citation
Sr. Lowry et al., IDENTIFICATION, CHARACTERIZATION, AND PHYSICAL MAPPING OF 14 POLYMORPHIC SIMPLE SEQUENCE REPEAT MARKERS ON HUMAN-CHROMOSOME-21, Genomics, 21(3), 1994, pp. 633-637
Citations number
16
Categorie Soggetti
Genetics & Heredity
Journal title
Genomics → ACNP
ISSN journal
08887543
Volume
21
Issue
3
Year of publication
1994
Pages
633 - 637
Database
ISI
SICI code
0888-7543(1994)21:3<633:ICAPMO>2.0.ZU;2-S
Abstract
Fourteen new dinucleotide repeat polymorphisms specific for human chro mosome 21 have been identified, mapped, and characterized. The average heterozygosity of all markers was 0.66. The average PIC value was 0.6 1. The markers were mapped by STS content mapping of YACs previously a ssigned to chromosome 21. The correlation of polymorphic genetic marke rs with substantially complete physical maps should facilitate the ide ntification of loci of interest on chromosome 21. (C) 1994 Academic Pr ess, Inc.