The symptoms of progressive dyspnea and strider in the setting of mali
gnant airway obstruction are severe and distressing. Conservative nebu
lizer and oxygen therapy offer little relief, and conventional stentin
g with T tubes requires a tracheostomy. In this article, we describe o
ur experience with stenting in the treatment of malignant mediastinal
disease using the Gianturco expanding metal-wire stents. The technique
of placement is simple and the procedure was successful in all 21 cas
es. Relief of strider was immediate and the dyspnea usually abated. Th
ese benefits continued through the mean survival period after stenting
of 134 days (range, 2 to 799 days). The patients required only brief
hospitalization (2.83 days) before returning home or to the referring
institution. It appears that expandable wire stents may offer a simple
yet effective intervention in the palliative treatment of mediastinal
malignancy.