ACTIVITY-DEPENDENT VARIATIONS IN CONDUCTION-VELOCITY OF C-FIBERS OF RAT SCIATIC-NERVE

Changes in the conduction velocity and subsequent conduction block wer e characterized following impulse activity in single C fibers of rat s ciatic nerves. C fibers which had the same resting conduction velociti es often exhibited quite different profiles of the activity-dependent latency change and/or conduction block following impulses. The results imply underlying variation among C fibers in the activity-dependent e xcitability changes, especially in the build-up and recovery of the hy poexcitable phases.