USE OF INTRAARTERIAL CHEMOTHERAPY IN THE TREATMENT OF MALIGNANT-TUMORS IN CHILDREN

Transcatheter arterial chemotherapy has been perfected in the treatmen t of 66 patients with various severe malignant tumors. A total of 75 a rterial cytostatic injections were made, out of them 57 were given in primary tumors and 18 in tumor metastases. The children's age ranged f rom 1 to 14 years. High arterial therapeutic doses in combination with extracorporeal blood purification by hemosorption in the treatment of hepatic metastases yielded 100 % efficiency. Prolonged arterial chemo therapy for pulmonary metastases provided an excellent therapeutic eff ect. Thus, 75 arterial injections of cytostatics gave rise to 32 % of complete remissions 48 % of partial remissions. There was no benefit i n 20 % of cases. Adverse reactions were absent.