TO THE PROBLEM OF DIFFERENTIAL-DIAGNOSIS AND TREATMENT OF METATYPIC CARCINOMA

Fifty one patients with metatypic carcinoma (MC), 10 with basalioma, a nd 10 with squamous cell carcinoma were clinically and immunomorpholog ically studied. There were great differences in the localization of ba sal cell antigen in the epidermis during MC, basalioma, squamous carci noma of the skin. Expression of fixed immunoglobulins A, M, G in tumor tissues revealed no significant differences. Fifty one patients under went a complex treatment with prospidine in a total dose of 3,000-3,50 0 mg (in a daily dose of 100 mg) followed by near-focus X-ray therapy in a total dose of 3,000 Gy (a single dose being 500 Gy). Good immedia te and late (the duration of the follow-up was as long as 5 years) res ults were obtained.