ANTIPSYCHOTIC EFFECTS AND TOLERANCE OF CRUDE RAUVOLFIA-VOMITORIA IN NIGERIAN PSYCHIATRIC-INPATIENTS

Authors
OBEMBE A SOKOMBA EN SIJUWOLA OA OLORUNFEMI PO ALEMIKA TOE ISICHEI CO OGUNKEYE OO BANGUDU AB
Citation
A. Obembe et al., ANTIPSYCHOTIC EFFECTS AND TOLERANCE OF CRUDE RAUVOLFIA-VOMITORIA IN NIGERIAN PSYCHIATRIC-INPATIENTS, PTR. Phytotherapy research, 8(4), 1994, pp. 218-223
Citations number
17
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
8
Issue
4
Year of publication
1994
Pages
218 - 223
Database
ISI
SICI code
0951-418X(1994)8:4<218:AEATOC>2.0.ZU;2-L
Abstract
The dried root of Rauvolfia vomitoria administered orally to 10 psychi atric patients at doses up to 800 mg/day, in divided doses, showed ant ipsychotic effects. The overall side effects were minimal, without ser ious incidence of extrapyramidal symptoms. Physical examination and la boratory parameters tend to correlate with the theory that Rauvolfia v omitoria accumulates in the plasma. The antipsychotic effects of Rauvo lfia vomitoria were shown to be dose dependent when given three-times a day, with minimal side effects.