NITRIC-OXIDE - FROM MEDIATOR TO MEDICINES

Authors
VALLANCE P MONCADA S
Citation
P. Vallance et S. Moncada, NITRIC-OXIDE - FROM MEDIATOR TO MEDICINES, Journal of the Royal College of Physicians of London, 28(3), 1994, pp. 209-219
Citations number
129
Categorie Soggetti
Medicine, General & Internal
Journal title
Journal of the Royal College of Physicians of London → ACNP
ISSN journal
00358819
Volume
28
Issue
3
Year of publication
1994
Pages
209 - 219
Database
ISI
SICI code
0035-8819(1994)28:3<209:N-FMTM>2.0.ZU;2-Q
Abstract
Nitric oxide is involved in a wide range of physiological processes in humans and in animals. It controls vascular tone, acts as a neurotran smitter and neuromodulator in the central and peripheral nervous syste ms and influences the activity of the immune system. Substances that s electively enhance or inhibit its synthesis or removal and modify its effects, are likely to yield interesting therapeutic agents.