DSM-III-R NICOTINE DEPENDENCE IN YOUNG-ADULTS - PREVALENCE, CORRELATES AND ASSOCIATED PSYCHIATRIC-DISORDERS

We describe the epidemiology of nicotine dependence and its associatio n with other substance use and PSYChiatric disorders. Data came from a random sample of young adults, 21-30 years of age, in the Detroit, Mi chigan metropolitan area. The NIMH Diagnostic Interview Schedule was u sed to ascertain DSM-III-R disorders. Lifetime prevalence of nicotine dependence was 20%. Higher rates were observed in whites, persons with low education and persons who were separated or divorced. Males and f emales with nicotine dependence had significantly increased odds for a lcohol and illicit drug disorders, major depression and one or more an xiety disorder, as compared to non-dependent smokers and non-smokers c ombined. Among smokers, lifetime Prevalence of illicit drug disorders other than marijuana alone, major depression and any anxiety disorder were significantly higher in dependent than non-dependent people. Majo r depression was associated specifically with nicotine dependence, an association explained in part by neuroticism. This finding suggests th at the personality trait of neuroticism might constitute a common pred isposition for major depression and nicotine dependence.