Occurrence of a similar cardiac malformation in multiple family member
s has been reported for many lesions. Neither tricuspid atresia nor tr
icuspid annular hypoplasia and tricuspid atresia has been described in
multiple members of the same family. We report two cases of tricuspid
atresia and one case of tricuspid annular hypoplasia with an atrial s
eptal defect in siblings. The findings in this family suggest an autos
omal recessive pattern of inheritance for abnormal tricuspid valve mor
phogenesis.